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Soy and Cholesterol

. Cholesterol is a soft fat. Cholesterol does not dissolve well in water. This weak ability of cholesterol to dissolve in water is a major factor in the development of atherosclerosis. The body gets cholesterol from food, but it is also produced by the body. Cholesterol is produced primarily in the liver, but also in the adrenal glands and reproductive organs. Cholesterol is a necessary component of your body cells and is a building material for hormones such as estrogen and testosterone. Cholesterol can cause problems when high levels are present in the bloodstream. These high levels lead to hardening of the arteries, leading to coronary heart disease and other vascular problems.

Soy may lower cholesterol

. Soy products help control cholesterol levels because:
  • soy is cholesterol-free
  • soy proteins lower cholesterol levels
  • Most of the fats in soy products are polyunsaturated.
  • Soy isoflavones prevent arteriosclerosis
  • Soy contains soluble fiber, which reduces the amount of cholesterol circulating in the blood.
Meta-Analyses of the Effects of Soy Protein Intake on Serum Lipids JW Anderson examined the relationship between soy protein consumption and serum lipid concentrations in humans in their meta-analysis of 38 controlled clinical trials involving more than 730 volunteers [1]. In most of these studies, animal protein was replaced with soy protein (47 g per day on average). Energy, fat and cholesterol intakes were similar between the control and soy-containing diets:
  • Replacing animal protein with soy protein reduced cholesterol by 9.3%.
  • Subjects on the soy diet reduced their LDL cholesterol by an average of 12.3%.
  • HDL cholesterol increased by 2.4% in subjects on the soy diet.
FDA Soy Health Claim The FDA cholesterol claim allows food manufacturers to claim that products containing more than 25 grams of soy protein per serving reduce the risk of heart disease.

References

[1] Meta-analysis of the effects of soy protein intake on serum lipids. N Engl J Med. 1995 Aug 3;333(5):276-82. Anderson JW et al.
[2] A meta-analysis of 46 FDA-identified studies demonstrates that soy protein reduces circulating LDL and total cholesterol concentrations. The Journal of Nutrition, Volume 149, Issue 6, June 2019. Sonia Blanco et al.

Comments

High cholesterol

hello,

i'm writing because i am now a soy consumer due to my high level of cholesterol (in the 300's). thank goodness soy happens to come in many tasty varieties. my question is this: to lower my bad cholesterol and maintain and aide my good cholesterol, how much soy should i be consuming per day in 'mg' and 'grams'. i'm hearing different portions from different sources. please set me straight. thank you in advance for your help.

also, should my 30 year old wife that does not have high cholesterol also be consuming as much soy as you recommend me to?

and finally, is soy milk (Trader joe's low fat brand)with 35 mg of isoflavons per serving a good idea?

extremely grateful,
ozzy
ozzy - 27/10/2013

Soy and cholesterol

Does soy cause your cholesterol go up especially ldl?
mmrsdab - 14/11/2013

Soy and cholesterol

A meta-analysis conducted in 1995 byAnderson concluded that the consumption of soy protein rather than animal protein significantly decreased serum concentrations of total cholesterol, LDL cholesterol, and triglycerides without significantly affecting serum HDL cholesterol concentrations (1). This study resulted in the approval by the FDA of the soy protein health claim. A more recent meta-analysis conducted in 2005 also showed that protein containing isoflavones significantly reduced serum total cholesterol, LDL cholesterol, and triacylglycerol and significantly increased HDL cholesterol (2). In the European Union, no protein health claim is yet approved by the EFSA. It is still not 100% clear which soy components - soy protein, isoflavones, fibers or polyunsaturated fatty acids - are responsible for the cholesterol lowering effects of soy.

(1) Meta-analysis of the effects of soy protein intake on serum lipids. N Engl J Med. 1995 Aug 3;333(5):276-82.
(2) Meta-analysis of the effects of soy protein containing isoflavones on the lipid profile. Am J Clin Nutr. 2005 Feb;81(2):397-408.
Rob - 14/11/2013

Can soy milk raise your triglycerides?

Can soy milk raise your triglycerides?
patty - 02/05/2014

Can soy milk raise your triglycerides?

There are no indications that the consumption of soy products, such as soy milk, will increase triglycerides. Many studies have confirmed the favourable effect of soy consumption on heart health. One study found that there is a suggestive body of evidence that soy and dietary phytoestrogens favorably alter glycemic control, improve weight and fat loss, lower triglycerides, low density lipoprotein cholesterol and total cholesterol (1).
Another study found no direct effect of soy milk consumption on triglycerides, but concluded that a 25 g dose of daily soy protein from soy milk led to a modest 5% lowering of LDL-cholesterol relative to dairy milk among adults with elevated LDL-cholesterol. The effect did not differ by type of soy milk and neither soy milk significantly affected other lipid variables, insulin or glucose (2).

(1) Soy, phytoestrogens and metabolism: A review. Mol Cell Endocrinol. 2009 May 25;304(1-2):30-42.
(2) Effect of two types of soy milk and dairy milk on plasma lipids in hypercholesterolemic adults: a randomized trial. J Am Coll Nutr. 2007 Dec;26(6):669-77.
Rob - 02/05/2014

my cholestrol level is high how can reduce

Plz help
chirag shah - 20/03/2015

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